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Other - Cost: £690,851,313.41 Sacubitril / Valsartan - Cost: £9,785,877.52 Trimbow - Cost: £12,179,561.00 Beclometasone / Formoterol MDI (Fostair) - Cost: £12,687,233.12 Empagliflozin (Jardiance) - Cost: £15,263,803.82 Edoxaban (Lixiana) - Cost: £17,888,346.00 Glucose interstitial detection sensor (FreeStyle Libre 2 Plus Sensor) - Cost: £19,428,975.00 Tirzepatide (Mounjaro KwikPen) - Cost: £22,912,812.00 Dapagliflozin - Cost: £32,605,964.38
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Notes for: Central nervous system
Last edited [10/12/2021 11:31:41]

‘Safety First: Five-Year Report of the National Confidential Inquiry into Suicide and Homicide by People with Mental Illness’ recommends that patients at risk of suicide, including all patients with a recent history of self-harm, who are treated with psychotropic drugs should receive modern, less toxic drugs and/or supplies lasting no more than 2 weeks.

 

Last edited [14/08/2025 16:18:35]

Cornwall Joint Formulary Recommended Choices     (...Top)
Displaying 15 Drugs

Key:
First Line Drugs First Line Drugs
Second Line Drugs Second Line Drugs
Specialist advised Specialist advised
Specialist Initiated Drugs Specialist Initiated Drugs
Hospital Only Drugs Hospital Only Drugs
Discouraged Discouraged
No comment available No comment available

NameTariffBNF Sub Paragraph
Pizotifen
0.5 mg tab Pack of 28
£1.21PCT FORMULARY STATUS: First Line Drugs Prophylaxis Of MigraineView BNF Article on 'Pizotifen'View SPC on 'Pizotifen'View PIL on 'Pizotifen'
Pizotifen
1.5 mg tab Pack of 28
£1.56PCT FORMULARY STATUS: First Line Drugs Prophylaxis Of MigraineView BNF Article on 'Pizotifen'View SPC on 'Pizotifen'View PIL on 'Pizotifen'
Rimegepant (Vydura)
75 mg oral lyophilisates tablets Pack of 2
£25.80PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] The initiation of Rimegepant for the prophylaxis of migraine (as per NICE TA 906) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Concomitant administration with strong CYP3A4 inhibitors or moderate or strong CYP3A4 inducers is not recommended. See BNF or SmPC for guidance on potential drug interactions.
 Prophylaxis Of Migraine
View BNF Article on 'Rimegepant'View SPC on 'Rimegepant'View PIL on 'Rimegepant'
The initiation of Rimegepant for the prophylaxis of migraine (as per NICE TA 906) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Concomitant administration with strong CYP3A4 inhibitors or moderate or strong CYP3A4 inducers is not recommended. See BNF or SmPC for guidance on potential drug interactions.
Rimegepant (Vydura)
75 mg oral lyophilisates tablets Pack of 8
£103.20PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] The initiation of Rimegepant for the prophylaxis of migraine (as per NICE TA 906) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Concomitant administration with strong CYP3A4 inhibitors or moderate or strong CYP3A4 inducers is not recommended. See BNF or SmPC for guidance on potential drug interactions.
 Prophylaxis Of Migraine
View BNF Article on 'Rimegepant'View SPC on 'Rimegepant'View PIL on 'Rimegepant'
The initiation of Rimegepant for the prophylaxis of migraine (as per NICE TA 906) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Concomitant administration with strong CYP3A4 inhibitors or moderate or strong CYP3A4 inducers is not recommended. See BNF or SmPC for guidance on potential drug interactions.
Atogepant (Aquipta)
10 mg tablets Pack of 28
£182.16PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] The initiation of Atogepant for the prophylaxis of migraine (as per NICE TA973) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Dosing reduction is required for concomitant use of specific strong CYP3A4 or OATP inhibitor drugs. See BNF or SmPC for guidance on potential drug interactions. Prophylaxis Of MigraineView BNF Article on 'Atogepant'View SPC on 'Atogepant'View PIL on 'Atogepant'
The initiation of Atogepant for the prophylaxis of migraine (as per NICE TA973) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Dosing reduction is required for concomitant use of specific strong CYP3A4 or OATP inhibitor drugs. See BNF or SmPC for guidance on potential drug interactions.
Atogepant (Aquipta)
60 mg tablets Pack of 28
£182.16PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] The initiation of Atogepant for the prophylaxis of migraine (as per NICE TA973) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Dosing reduction is required for concomitant use of specific strong CYP3A4 or OATP inhibitor drugs. See BNF or SmPC for guidance on potential drug interactions. Prophylaxis Of MigraineView BNF Article on 'Atogepant'View SPC on 'Atogepant'View PIL on 'Atogepant'
The initiation of Atogepant for the prophylaxis of migraine (as per NICE TA973) by GPs who are confident to do this without specialist input is accepted. (Adults who have at least 4 migraine attacks per month, only if at least 3 preventative treatments have not worked or are unsuitable.) Dosing reduction is required for concomitant use of specific strong CYP3A4 or OATP inhibitor drugs. See BNF or SmPC for guidance on potential drug interactions.
Erenumab (Aimovig)
70 mg/1ml solution for injection pre-filled pens Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Prophylaxis Of MigraineView BNF Article on 'Erenumab'View SPC on 'Erenumab'View PIL on 'Erenumab'
Erenumab (Aimovig)
140 mg/1ml solution for injection pre-filled pens Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Prophylaxis Of MigraineView BNF Article on 'Erenumab'View SPC on 'Erenumab'View PIL on 'Erenumab'
Fremanezumab (Ajovy )
225 mg/1.5ml solution for injection pre-filled pens Pack of 1
- PCT FORMULARY STATUSHospital Only Drugs Prophylaxis Of MigraineView BNF Article on 'Fremanezumab'View SPC on 'Fremanezumab'View PIL on 'Fremanezumab'
Fremanezumab (Ajovy )
225 mg/1.5ml solution for injection pre-filled syringes Pack of 1
- PCT FORMULARY STATUSHospital Only Drugs Prophylaxis Of MigraineView BNF Article on 'Fremanezumab'View SPC on 'Fremanezumab'View PIL on 'Fremanezumab'
Galcanezumab (Emgality )
120 mg/1ml solution for injection pre-filled pens Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Prophylaxis Of MigraineView BNF Article on 'Galcanezumab 'View SPC on 'Galcanezumab 'View PIL on 'Galcanezumab '
Topiramate
25 mg tab Pack of 60
£1.49PCT FORMULARY STATUSNo comment available Prophylaxis Of MigraineView BNF Article on 'Topiramate'View SPC on 'Topiramate'View PIL on 'Topiramate'
When used for prophylaxis of migraine, topiramate may be specialist-advised. Topiramate is now contraindicated in women of childbearing potential unless the conditions of the pregnancy prevention programme are met. Please see the MHRA website for further details of the new safety measures including the pregnancy prevention programme.
Topiramate
50 mg tab Pack of 60
£2.13PCT FORMULARY STATUSNo comment available Prophylaxis Of MigraineView BNF Article on 'Topiramate'View SPC on 'Topiramate'View PIL on 'Topiramate'
When used for prophylaxis of migraine, topiramate may be specialist-advised. Topiramate is now contraindicated in women of childbearing potential unless the conditions of the pregnancy prevention programme are met. Please see the MHRA website for further details of the new safety measures including the pregnancy prevention programme.
Topiramate
100 mg tab Pack of 60
£2.53PCT FORMULARY STATUSNo comment available Prophylaxis Of MigraineView BNF Article on 'Topiramate'View SPC on 'Topiramate'View PIL on 'Topiramate'
When used for prophylaxis of migraine, topiramate may be specialist-advised. Topiramate is now contraindicated in women of childbearing potential unless the conditions of the pregnancy prevention programme are met. Please see the MHRA website for further details of the new safety measures including the pregnancy prevention programme.
Topiramate
200 mg tab Pack of 60
£10.19PCT FORMULARY STATUSNo comment available Prophylaxis Of MigraineView BNF Article on 'Topiramate'View SPC on 'Topiramate'View PIL on 'Topiramate'
When used for prophylaxis of migraine, topiramate may be specialist-advised. Topiramate is now contraindicated in women of childbearing potential unless the conditions of the pregnancy prevention programme are met. Please see the MHRA website for further details of the new safety measures including the pregnancy prevention programme.

 
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